Mouhannad Malek


Published Papers:

1- Malek M, Guillaumot P, Huber AL, Lebeau J, Pétrilli V, Kfoury A, Mikaelian I, Renno T, Manié SN. LAMTOR1 depletion induces p53-dependent apoptosis via aberrant lysosomal activation. Cell Death and Disease (2012) PMID: 22513874.
2- Alduhishy M, Malek M. Correspondence: “Middle East: Popular uprising spreads science” Nature. (2015)
3- Kiselev V*, Juvin V*, Malek M, Luscombe N, Hawkins P, Le Novère N, Stephens LR. Perturbations of PIP3 signalling trigger a global remodelling of mRNA landscape and reveal a transcriptional feedback loop. Nucleic Acid Research Journal (2015)
4- Li H, Wu X, Hou S, Noh S, Malek M, Kielkowska A, Makondo KJ, Du Q, Wilkins J.A, Johnstond JB, Gibson S.B, Lin F, and Marshall AJ. Phosphatidylinositol-3,4-biphosphate and its binding protein lamellipodin regulate chemotaxis of malignant B lymphocytes. Journal of Immunology.
5- Yakoub S, El-Chami N, Kaszas C, Malek M, El Sirkasi M, Smith C, Baydoun E, Tabone E, Manié SN, Régnie. The Proto-Oncoprotein c-Cbl Protects Cells against Oxidative Stress by Down- Regulating Apoptosis and is Highly Expressed in Several Cancers. Journal of Cancer Science & Therapy (2014)
6- Juvin V, Malek M, Anderson K, Dion C, Chessa T, Lecureuil C, Ferguson J, Cosulich S, Hawkins P, Stephens L. Signaling via Class IA phosphoinositide 3-kinases (PI3K) in human, breast-derived cell lines. Plos One (2013) PMID: 24124465.
7- Mikaelian I, Malek M, Viallet J, Garcia A, Girard-Gagnepain A, Hesling A , Gillet A,Gonzalo P , Rimokh R, Billaud M , Gadet R. Genetic and pharmacologic inhibition of mTORC1 promotes EMT by TGF-ß independent mechanism. Cancer Research (2013) PMID:24078802.
8- Huber AL, Lebeau J, Guillaumot P, Pétrilli V, Malek M, Chilloux J, Fauvet F, Payen L, Kfoury A, Renno T, Chevet E, Manié SN. p58(IPK)-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose. Molecular Cell (2013) PMID:23395000.
9- De Falco V, Tamburrino A, Ventre S, Castellone MD, Malek M, Manié S, Santoro M. CD44 proteolysis increases CREB phosphorylation and sustains proliferation of thyroid cancer cells. Cancer Research (2012) PMID: 22271686.
10- Guillaumot P, Luquain C, Malek M, Huber AL, Brugière S, Garin J, Grunwald D, Régnier D, Pétrilli V, Lefai E, Manié SN. Pdro, a protein associated with late endosomes and lysosomes and implicated in cellular cholesterol homeostasis. Plos One (2010) PMID:20544018.

الأقسام: هل تعلم والإنفوغرافيك

آخر عمل: 23/08/2018 (تفاضلات العيد)




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